Developing organized level of biomedical evidence: evidence-based biomedicine

Evidence-Based Medicine (EBM) is a methodological and systematic approach, which is considered as the most robust form of the empirical medicine as it sorts evidence according to their credibility. It is widely used in clinical decision-making and has several advantages, including: (1) provision of a very well-founded and objective method to adhere to high quality and safety standards in medical practice, (2) facilitation of translation of clinical research findings into clinical practice, and (3) significant reduction of health care costs. EBM can be summarized into five practical steps include searching for an answer to a clinical question, searching for the evidence, critically appraising and reviewing the existing evidence, combining credible evidence with clinical experience and the patients’ viewpoints, and finally, evaluating the process. As it is widely believed that evidence is not properly classified and there is no credible assessment method in data on biomedical literatures, it could be suggested that EBM is of limited use in this branch of science (Clancy and Cronin, 2005). Therefore, in biomedicine, although there are literature redundancies and large number of evidences, they are only useful if a systematic searching approach is taken. Moreover, a structured process needs to be in place to analyze the findings and critically appraise them. Due to the existence of overwhelmingly disorganized data in the field of biomedicine that lead to non-categorized and non-screened information, it could be suggested that there is a need for development of a novel methodology considering different levels of evidence (Ioannidis, 2005; Cho, 2007). Moreover, the hierarchy of EBM in biomedicine is questionable; the need is more highlighted (Mantzoukas, 2008). Evidence Based Bio-Medicine (EBBM) can be considered as a novel method in biomedical literatures. This technique focuses on the evaluation and ranking of different articles with widely available techniques in the field based on their credibility, limitations, and biases. The aim of this letter is to analyze the effectiveness of EBBM in order to shed some light on its limitations. It could lead to classification of evidence on biomedical science issues and facilitate their practical application with the view of addressing the raised issue in this letter. In order to present the case more clearly, the following examples are used: